The hypnotics from the group of cyclopyrrolons, structurally different from benzodiazepines and barbiturates. Has a sedative, hypnotic effect, which are due to a high degree of affinity for binding sites at the GABA receptor complex in the central nervous system. Rapidly causes sleep, without decreasing the phase of fast sleep in its structure, and then maintains sleep with the preservation of the normal phase composition. Does not cause postsomnicheskih violations: there is no feeling of weakness and drowsiness on the morning of the next day.
Sleep occurs within 30 minutes and lasts 6-8 hours. Reduces headaches. In patients with nocturnal seizures of bronchial asthma, the combination of Zopiclone with LS of the methylxanthine series (theophylline) reduces asthma attacks in the early morning hours, reduces their intensity and duration.
Sleep disturbances (difficulty falling asleep, frequent nocturnal awakenings, early awakening), transient, situational and chronic insomnia; sleep disorders in mental disorders, bronchial asthma with night attacks (in combination with a one-time intake of a daily dose of theophylline).
On the part of the digestive system: a sensation of bitter or metallic taste in the mouth, dry mouth, nausea, vomiting.
From the side of the central nervous system: dizziness, headache, drowsiness, confusion, anterograde amnesia, hallucinations, nightmares.
Dermatological reactions: skin rash.
- With caution appoint for severe hepatic insufficiency.
- The risk of drug dependence is minimal if the duration of zopiclone application does not exceed 4 weeks. However, there is a potential danger of dependence on zopiclone.
- During the treatment should be excluded from drinking alcohol.
- Impact on the ability to drive vehicles and manage mechanisms.
- The next day after taking the drug, you should carefully drive the car and work with the mechanisms.
Dosing and Administration
Inside, 7.5 mg Zopiclone, 30-40 minutes before the proposed sleep, if necessary – up to 15 mg (maximum dose). The initial dose for the elderly and the maximum recommended dose for hepatic insufficiency is 3.75 mg. Duration of treatment with Zopiclone – no more than 1 month.
The number of tablets you need to take will depend on your condition. Zopiclone Tablets should be swallowed whole without sucking, chewing or crushing, with a small glass of water before you go to bed. The recommended dose is:
The usual adult dose is one Zopiclone Tablet (7.5mg) per day.